These duplications most commonly occur in one of two forms. These include an extra isodicentric 15 chromosome, abbreviated idic(15), or an interstitial duplication 15, abbreviated int dup(15). When the duplicated material comes from the maternal chromosome, developmental problems are often the result. In most cases of chromosome 15q duplication syndrome, the chromosome duplication is not inherited, but occurred as a random event during the formation of reproductive cells.
We did it! We raised more than $55,000 this summer to get our mice to their behavior studies in California. A huge thank you to the more than 300 families who participated. Together we CAN make a difference!
For the past two years, researchers at Texas A&M University have worked to create a group of mice with increased levels of UBE3A, a key gene in dup15q syndrome. Now the mice are ready for the next step - behavior studies at the University of California Davis. It's a long, expensive journey. Please help us get our mice to California, by making a donation today!
1st Annual Jax Jubilee
Family Movie Night
Cynthia Morales decided to run the NYC Marathon to mark the milestone of turning 40. I love my two nieces and two nephews. These wonderful kids make me strive to be a good role model and a good person. Instead of having a big party, I thought I would bring meaning to my birthday and my training by focusing on my youngest nephew, C.J. who has special needs. For my 40th birthday, I would love to raise $4,000 to help other kids like my nephew who has chromosome 15q11.2-13.1 duplication syndrome (dup15q or dup15q syndrome). The funds raised will go to the Dup15q Alliance (www.dup15q.org).
When my nephew was diagnosed, doctors informed my sister that he would never learn to speak and that the manifestations of this syndrome would be unknown. C.J. has his difficulties. Although 5 years old, he can be confused like a three year old. Yet this kid always is smiling, happy and positive. He challenges us to remember what is important in life by always maintaining a positive attitude. Despite the early ominous warnings from the doctor, C.J. is verbal and very active. He loves chasing his dog and playing with all kinds of balls.
Please help me stay motivated to train through the heat and humidity of the summer in Miami. I am dedicating my participation in the NYC Marathon to C.J. Instead of all birthday presents (except for candy), please consider giving a small donation (equal to the price of a beer, glass of champagne or other beverage to toast for my birthday) for my birthday!More information