These duplications most commonly occur in one of two forms. These include an extra isodicentric 15 chromosome, abbreviated idic(15), or an interstitial duplication 15, abbreviated int dup(15). When the duplicated material comes from the maternal chromosome, developmental problems are often the result. In most cases of chromosome 15q duplication syndrome, the chromosome duplication is not inherited, but occurred as a random event during the formation of reproductive cells.
Dylan Ritter, whose brother has dup15q syndrome, earned a coveted spot in the lab of Dr. Scott Dindot, one of the leading researchers on dup15q syndrome. Read this news story about Dylan and how he's working to find treatments for his brother's disorder.
Dup15q Alliance is please to announce that Dr. Dimitrios Arkilo of the Minnesota Epilepsy Group has joined the Professional Advisory Board. Dr. Arkilo is the director of the dup15q clinic in St. Paul, Minnesota.
A recent documentary on innovation at Geisinger Health System, home to one of the dup15q clinics, features a segment on treating those with dup15q syndrome at around the six minute mark.